
For thousands of years, turmeric root has been used as a tratitional Indian medicine. The turmeric spice, which gives curry its golden color, has been recognized for wide-ranging health benefits. The most beneficial compounds in turmeric are curcuminoids, which include curcumin and related compounds.
One animal study showed lifespan extension up to 26% with curcumin supplementation. But, there’s been a major problem that limits practical use: curcuminoids have poor oral bioavailability. That means a large portion of curcumin taken orally never gets absorbed into the blood stream and doesn’t reach the tissues.
Scientists have made a major advance in solving this problem. At Life Extension, we have perfected a patented form of curcumin that dramatically boosts its bioavailability. For the fist time, people have the opportunity to realize the potential of curcumin to benefit whole-body health, slow certain aging processes, and reduce risks for age-related disorders.
Extending Healthy Lifespan
By improving the absorption and tissue distribution of curcumin, it is now possible to maximize its benefits in fighting specific diseases. Perhaps the most remarkable ability curcumin has shown in research is to
How does it work? In studies of longevity, a handful of key mechanisms keep coming up. Each of the following has repeatedly been shown to help slow the aging process and extend healthy lifespan:
- Reducing chronic, low-grade inflammation
- Increasing activity of sirtuins specialized proteins that regulate cellular health.
- Decreasing activity of mToR, a protein associated with rapid aging and cancer.
- Enhancing activity of the enzyme AMPK, which improves metabolism.
- Boosting autophagy, the cellular “recycling” process that helps keep cells rejuvenated, and
- Protecting against tissue damage caused by glycation, when sugars attach to proteins and fats.
Curcumin positively affects every one of these targets.
Curcumin’s Effects on the Diseases of Aging
Curcumin has also been shown to be beneficial against many specific diseases and conditions. Among them are some of the most common and well-studied disorders, including the following;
- Neurodegenerative Diseases; age-related neudegenerative diseases and dementias, including Alzheimers disease.
- Cancer: In addition to reducing chronic inflammation and oxidative damage caused by free radicals, both of which contribute to the developemnt of cancer, curcumin has been shown to have anti-cancer effects.
- Obesity: Being overweight increases the risks of developing conditions like heart disease, stroke, cancer, and diabetes. By improving metabolic function and reducing inflammation, curcumin helps ameliorate some of these effects. it has also been found to aid in weight loss, as seen with calorie-restricted diets and exercise.
- Metabolic Syndrome: Metabolic Syndrome refers to a group of disorders, including elevated levels of blood surag, abnormal lipid profiles, high blood pressure, and excess belly fat. Curcuin has a powerful impact on metabolism, helping to reduce these risk factors.
- Cardiovascular Disease; Curcumin protects the heart and blood vessels in numerous ways. As noted, it can reduce risk factors for cardiovascular disease, like obesity, high blood pressure, and abnormal blood lipid levels. Curcumin also does much more. Research has shown that it can reduce pathological changes in the blood vessels and heart that contribut to atherosclerosis, aneurysm formation ad heart dysfunction.
- Arthritis: A powerful anti-inflammatory, curcumin is a way to treat painful ailments related to inflamation. One of the most common of thees conditions is osteoarthritis, the degenerative joint disease that occurs frequently in older age.

- Depression and Anxiety; Several studies have found that curcumin can help control symptoms of major deperssion.
- Source: Excerpts form Life Extension Magazine, February 2020


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